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Jacobsen EA, Ochkur SI, Lee NA, Lee JJ

Glutathione peroxidase and glutathione reductase activities are partially responsible for determining the susceptibility of cells to oxidative stress

Wade MJ, Bucci K, Rochman CM, Meek MH

Hodge J

Indeed, when we measured cholesterol and oxysterol derivatives with mass spectrometry, we found reduced levels of these species in rSCC-61 ( Figure 6B ) consistent with the model predictions, which we rationalized was driven by the ~15-fold higher squalene measured in rSCC-61 ( Supplementary Dataset S1 )