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A 20 percent change from baseline is generally considered meaningful based on power analysis of the published data, but detecting this requires sufficient sample consistency

10.1016/j.cell.2014.01.064 Cell 37 MattaS.Van KolenK.da CunhaR.van den BogaartG.MandemakersW.MiskiewiczK.et al
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Many foods contain vitamin B12, but not everyone eats enough of these foods
