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10.1371/journal.pone.0162590 [DOI] [PMC free article] [PubMed] [Google Scholar] Lovric-Bencic M., Sikiric P., Hanzevacki J

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(ii) Adjusting the stopper size typically fine-tunes the dethreading kinetics

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The liquid form or the lyophilizate powder form of the composition of the present invention may be dissolved or dispersed in a solution of a biodegradable polymer such as poly(lactic-glycolic) acid copolymer, poly(hydroxybutyric acid), poly(hydroxybutyric-glycolic) acid copolymer, or the mixture of these, and then may be formulated, for example, to films, microcapsules (microspheres), or nanocapsules (nanospheres), particularly in the form of soft or hard capsules