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Description
Maly JJ

The body excretes excess B12, and no upper tolerable limit has been established by UK or European regulatory authorities
Manipulation of the microbiota for treatment of IBS and IBDchallenges and controversies

These types of models are commonly used to investigate how signaling molecules influence coordinated repair responses rather than isolated cellular processes

His work focuses on how microbial ecosystems interact with human physiology, including: Gut barrier function and intestinal permeability Mucus-associated microbiota (Akkermansia-related systems) Oralgut microbiome axis Short-chain fatty acids (SCFAs) and metabolic signaling Circadian rhythmmicrobiome interactions Clinical Research Contributions He has contributed to multiple clinical-stage microbiome programs, supporting bacterial strain discovery, optimization, and formulation design across different therapeutic areas, including: Active Ulcerative Colitis (Inflammatory Bowel Disease) Hyperoxaluria (Oxalate Metabolism Disorder) Microbiome-driven gut health and inflammatory conditions These studies were part of broader clinical development programs evaluating microbiome-based approaches

The ones who succeed won't be the ones with the most compelling peptide lineup
