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The p53-S100A2 positive feedback loop negatively regulates epithelialization in cutaneous wound healing

Gut Microbiota-Epithelial Barrier Interplay The human gut harbors a community of about 10 14 microorganisms resulting from thousands of years of co-evolution with the host, with an intricate and mutually beneficial relationship (169)

Mixing them creates stability and degradation risks that eliminate the clinical benefit of either compound

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In fact, a B12 deficiency can sometimes lead to weight loss due to reduced appetite
