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Because -glutamyl transpeptidase is a plasma membrane-bound enzyme with its active site on the extracellular surface of the membrane, export of GSH and its adducts into the extracellular space is the initial, and presumably regulated step in their turnover in all mammalian cells

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2022 doi: 10.1089/can.2022.0008

Researchers have been intrigued by the promising anticancer effects exhibited by DAT, leading to a growing interest in exploring its therapeutic applications in the field of oncology ( DMOCPTL is a derivative of the natural product parthenolide found in plants like feverfew

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Form Reconstituted vial Temperature 35.6 to 46.4 F (2 to 8 C) Note Refrigerate