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4 Research estimates that MCAS may affect up to 17% of the population to some degree, though many cases go undiagnosed

The cochleas unique anatomical and physiological characteristics, such as high metabolic activity and limited blood supply, make it particularly susceptible to oxidative damage

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For instance, MDSCs promote tumor immune escape by inhibiting NK and CD8+ T cell activity in the tumor microenvironment, a function similarly exhibited by Tregs (177, 178)