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Evodiamine exhibits anti-bladder cancer activity by suppression of glutathione peroxidase 4 and induction of ferroptosis

The CypB and Hsp70 amino acid phylogenetic analysis of B

Haematologica 108 (2), 353366

doi: 10.1158/1078-0432.CCR-12-0708 88 TorphyRJSunYLinRCaffrey-CarrAFujiwaraYHoFet al

These include regulation of mechanisms controlling reactive oxygen species (ROS), which cause macromolecular damage 16,17 , mitochondrial turnover or mitophagy 18 , and the mitochondrial unfolded protein response (UPR mt ), in which mitochondrial damage can be prevented by the removal of aggregated or unfolded proteins 19
