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Patients with colorectal cancer have identical strains of Fusobacterium nucleatum in their colorectal cancer and oral cavity

PPP, Pentose Phosphate Pathway

Also, a high dose of green tea extract caused renal toxicity and hepatotoxic effects 12,15,19

Melatonin increases the expression of cadherins (E-cadherin) by preventing the interaction of NF- with the junctional enhancer protein CCAAT (C-EBP), integrins (1-integrin) by reducing the expression of v3 integrin, occludin (tight junctions) [28,29] and vimentin, proteins involved in cell adhesion, migration, and invasiveness

Mackin, S

Once ulceration develops, the lesions become colonized by the local flora which can further aggravate the injury and impair healing