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Pb has been shown to activate astrocytes and microglia, leading to the release of pro-inflammatory cytokines such as interleukin-1 (IL-1) and tumor necrosis factor-alpha (TNF-) [99]

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The thiol group of glutathione is embedded in a hydrophobic/aromatic pocket composed of Q61, Y63, F67, K122, Y126, and W224 (Fig

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