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rather, they reflect a gradual, systemic loss of adaptability that reduces the capacity of older adults to tolerate physical, metabolic, and environmental stressors (Lutz and Quinn, 2012)

This indicates that alterations in intestinal epithelium integrity caused by genetic or environmental factors contributes to the translocation of luminal microbes that can become immunogenic when delocalised from their GI niche (Fine et al
N., Jiang, Y

Feng L, Wu D, Lin J, Li Y, Zhao Y, Zhang P, Yao Y, Fu S

Moreover, Malassezia spp
