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Lee J, Hudson MR, OBrien TJ, Nithianantharajah J, Jones NC

P., Jorge, G

Regarding mechanical components, tumor matrices are stiffer due to higher collagen production from stromal cells, and these collagen levels have been linked to Rho/ROCK and FAK regulation ( Unlike in the TME where angiogenesis is upregulated, some diseases are caused by or related to inhibited blood vessel growth, function, or survival

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Tumor heterogeneity in glioblastomas: from light microscopy to molecular pathology

This cysteine is also evolutionarily conserved and specifically S -nitrosylated in both human and fly NADPH oxidases, suggesting that this mechanism may govern immune responses in both plants and animals (Yun et al., 2011)