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Peptide therapeutics: Current status and future directions
Vitamin B6 (Pyridoxine) acts as a necessary cofactor in the folate cycle and combines with serine hydroxymethyl transferase to effect the conversion of tetrahydrofolate(THF) to 5,10 methylene THF (14)
During this conversion, our bodies are left with cyanide as a byproduct, which must be detoxified and eliminated by the liver (15)
DOI: 10.1186/s12875-025-03036-0
These findings suggest oral administration can be effective, at least in rodent models
