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In a prospective double-blind study of euthyroid subjects (6074 years old) receiving a seleniumyeast-based supplementation (100, 200, or 300 g Se/day for 5 years), decreases in serum TSH and fT4 concentrations but no changes in fT3 or the FT3/fT4 ratio were observed, indicating a dose-dependent effect on thyroid function even in healthy individuals [39]

Tau is required for progressive synaptic and memory deficits in a transgenic mouse model of -synucleinopathy

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van der Windt GJ, Everts B, Chang CH, Curtis JD, Freitas TC, Amiel E, et al

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Various data collection methods including PubMed, Scopus, ResearchGate, and Google Scholar were used to collect relevant research papers using keywords changes caused by fluoride in thyroid or fluoride induced toxicity on the thyroid gland ranging from 1976 till date