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Epithelial cells from Lgr5 DTR-EGFP/+ organoids were gated as EpCAMCD45 CD31 Ter119 7AAD , and Lgr5-EGFP fluorescence intensity was used to classify cells into GFPhigh and GFPneg populations, where the GFPneg gate was defined based on the background fluorescence intensity of WT control organoids lacking EGFP expression

BPC-157 and TB-500 are the two most studied tissue-repair peptides in preclinical research, and the pairing is popularly nicknamed the "Wolverine stack" after the comic-book character known for rapid healing

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Large injection volumes can cause localized reactions, particularly stinging or a raised bump at the injection site

[DOI] [PMC free article] [PubMed] [Google Scholar] 22.Miller J.W

10.1590/s0102-865020190070000008 222 WeiY