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In humans and L-gulonolactone oxidase mutant mice studies, ascorbate promoted TET2-dependent 5hmC formation allowing normal differentiation while ascorbate or TET2 deficiency allows HSCs to proliferate resulting in leukaemia [140], [141], [142]
2021 Feb;9(1):100298
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It helps protect against age-related concentration impairment, supports long-term heart and brain health
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