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This upregulation may link the interaction between increased oxidative stress and immunological overactivation

This study explores MTH1s potential as a therapeutic target, particularly in cancer treatment, providing insights into its structure, function, and role in disease progression

Shen H, Tsuchida S, Tamai K and Sato K

Upon activation, the NLRP3 inflammasome promotes autocatalytic cleavage of procaspase-1 into its active form, caspase-1, which subsequently processes the pro-inflammatory cytokines pro-interleukin-1 and pro-interleukin-18 into their mature forms

105 The decreased secretion of nutrient factors by bone marrow stromal cells can result in an enhanced differentiation of HSCs into myeloid cells and a reduced differentiation into lymphocytes

Bendhack, Lusiane M
