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The findings not only deepen our understanding of PCOS pathogenesis but also establish a strong theoretical foundation for innovative microbiome-based therapeutics

Contractor R, Samudio IJ, Estrov Z, Harris D, McCubrey JA, Safe SH, Andreeff M , Konopleva M

Am J Physiol Endocrinol Metab (2014) 307:E6170

Adhesions are a known source of reduced tendon mobility, although they are difficult to anticipate after surgical correction [50]

B-class plexins regulate several small GTPases, interacting with Rac [21], Rnd1-2-3 [22], R-Ras [23], M-Ras [24] and RhoD [25] and regulating Rho via PDZRhoGEF/LARG [26] and p190RhoGAP [27]

The genomic convergence of these features underscores the potential role of pharmaceutical wastewater as a reservoir for high-risk bacterial lineages and highlights the need for improved wastewater treatment and enhanced environmental surveillance