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Cartilage, which is a living tissue, is characterised by a flexible yet resistant structure made up of several components: 70 to 80% water collagen fibres for resistance and solidity, Hyaluronic acid for elasticity, proteoglycans (glucosamine and chondroitin) which can be compared with water reservoirs for shock absorption

doi.org/10.3389/fendo.2023.1148556 Unfer V, Facchinetti F, Orr B, Giordani B, Nestler J

However, some studies have focused on a specific metabolic pathway of interest without considering overall metabolic changes

WASF3 belongs to a family of genes with homology to the WiskottAldrich Syndrome (WAS) gene which when mutated can cause the rare X-linked immunodeficiency disorder associated with B cell dysfunction (65)

Spot A (MW ~28, pI ~6.3), which was decreased after treatment (t 10 =2.27, P =0.047, Fig

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