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in vivo , whereas SLC7A11 / embryonic fibroblasts underwent cell death in routine culture medium in vitro but could proliferate normally in the presence of 2-mercaptoethanol (2ME), N-acetyl cysteine (NAC), or vitamin E (Stipanuk, 2004
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The Nrf2-mediated protective response is increased under elevated CYP2E1 expression in liver cells [17]
Furthermore, IGFBP3 has been shown to exhibit antiproliferative and proapoptotic actions via an IGF-1/IGF-1R-independent mechanism [103]
Upregulation of glutaredoxin-1 activates microglia and promotes neurodegeneration: implications for Parkinsons disease
