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The protocol for the use of patient samples in this study was approved by the Human Subjects Committee of Tongji Hospital (Clinical trial registration number: Lunwei-KYSB-2016-103)

doi: 10.3389/fimmu.2020.591803

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During the latter, GSH acts as a reducing agent and donates an electron in the presence of the enzyme glutathione peroxidase (GPx), thereby giving rise to its oxidized form, GSSG (Higuchi, 2014)