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Br J Pharmacol 138(7):12071209

These compounds, in fact, interact only transiently with the target protein leading to scarce effects

M.MelaV.Rubio-AraizA.TimmonsG.et al

(3) Vesicular displacement: Tyramine is transported into synaptic vesicles through vesicular monoamine transporter 2 (VMAT2), displacing norepinephrine (NE) from vesicular storage sites into the cytoplasm

Sigma-Aldrich, NM_018444: SASI_Hs01_00128068) were transfected into hPSCs using Lipofectamine 2000 (Thermo Fisher Scientific, 11,668037), following the manufacturers instructions

However, in schizophrenia, reduced CBF impairs this process, exacerbating neuronal damage and cognitive deficits, including auditory verbal hallucinations (AVHs) (126)