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10.1016/j.bioactmat.2025.02.021 19 CassidyJ

Mechanisms of mitochondrial ROS overproduction in NAFLD: Mitochondria are a central source of reactive oxygen species (ROS) in non-alcoholic fatty liver disease (NAFLD), primarily due to electron leakage at complexes I and III of the electron transport chain (ETC)

L-carnitine is a form of carnitine present in the body and many supplements

Invest New Drugs 31(2):333344 Ming Z, Wotton CA, Appleton RT, Ching JC, Loewen ME, Sawicki G et al (2015) Systemic lipopolysaccharide-mediated alteration of cortical neuromodulation involves increases in monoamine oxidase-a and acetylcholinesterase activity

Hericenones and erinacines: Stimulators of nerve growth factor (NGF) biosynthesis in Hericium erinaceus

Furthermore, the model can simulate a variety of stimuli to neurons to guide studies on the energy constraints of brain activity