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To view a copy of this license, visit About this article Cite this article Kitamura, S., Katayose, Y., Nakazaki, K

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While these studies present intriguing possibilities for promoting longevity and improving health span, the broader scientific community awaits more extensive, large-scale clinical trials to fully validate these findings and understand its complete physiological impact

In addition, transforming growth factor-1 (TGF-1), a potent fibrogenic protein, is known to upregulate astrocyte synthesis of proteoglycans causing severe gliosis (Yin et al., 2009