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The authors observed significant morphological changes in mitochondria in the cochlear tissue of aged mice, including cristae alterations, mitochondrial vacuolization, OMM rupture, and autophagosome increase, whereas most genes regulating mitophagy, including Parkin, PINK1, BNIP3, BNIP3L/NIX, and FUNDC1, were downregulated in an age-dependent manner

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Mononeuropathy Mononeuropathy refers to the damage of a single or a group of nerves, resulting in localized symptoms such as pain, weakness, or sensory loss in the affected area

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