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Activation of BECs by increasing the level of adhesion molecules has been shown to play a role in the recruitment of leukocytes to the CNS

In OA patients with a nociplastic pain component undergoing total joint arthroplasty, surgical removal of the presumed peripheral source led to pain resolution in approximately twothirds of patients, consistent with a dominant bottomup mechanism

10.1080/10408398.2021.1917508 36 ChenM.WangR.WangT

Investigating the metabolism of glucoraphanin by the human gut microbiota using ex vivo culturing methods

Under normal conditions, GPX4 reduces lipid peroxides, preventing ferroptosis