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All MD simulations were performed with the program package GROMACS (version 2020.4) 32 using the GROMOS 54a7 force field 33

The molecule is unambiguous

A direct comparison between the two methods for analysis of GSH and GSSG in several mouse tissues has been performed also recently [15]

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Acknowledgements We sincerely thank Ya-Hui Tsai, PhD, research specialist in the Division of Pediatric Surgery, Department of Surgery, Far-Eastern Memorial Hospital for editing the figures in the manuscript