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2.Allison DB, Fontaine KR, Manson JE, Stevens J, VanItallie TB

They may reduce the risk of heart disease, strokes, and kidney problems

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Important Safety Information Contraindications and Precautions: Joint injections should only be performed by qualified medical professionals Active joint infection is an absolute contraindication to intra-articular injection Bleeding disorders or anticoagulation therapy may increase injection risks Pregnancy and breastfeeding: no safety data available, avoid use Cancer history: while AOD-9604 does not affect IGF-1, consult oncologist before use Monitoring Recommendations: Regular follow-up with joint imaging and functional assessments to evaluate treatment response

The 5 mg vial format supports controlled experimental design, formulation studies, and dose-range exploration