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Retatrutide is a novel triple agonist of the glucose-dependent insulinotropic polypeptide, glucagon-like peptide 1 and glucagon receptors

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TRIUMPH-1 TRIUMPH-1, a randomized, placebo-controlled phase 3 study, assessed the safety and efficacy of weekly retatrutide on weight reduction and health in adults with obesity or overweight, including subsets of participants with obstructive sleep apnea (OSA) or knee osteoarthritis (OA)

It is recommended to avoid alcohol

It works by mimicking the actions of glucagon-like peptide-1 (GLP-1), a natural hormone that suppresses your appetite, slows digestion, and keeps you feeling satisfied for longer

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