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An important contributor to the systemic distribution of metabolites is recycling of glucuronides that are eliminated via bile or directly into the intestinal lumen

Ascorbate, also called Vitamin C, has been known to have the ability to neutralize superoxide radicals (44, 60)

It is equipped with the enzymes and metabolic pathways required to produce this vital vitamin

Probiotic Bifidobacterium species stimulate human SLC26A3 gene function and expression in intestinal epithelial cells

According to different protein metabolism pathways, ferroptosis-related genes are divided into four categories: genes related to iron metabolism, which include ACO1 (aconitase 1), CISD1 (CDGSH iron-sulfur domain-containing protein 1, also termed mitoNEET), FANCD2 (FA complementation group D2), FTH1 (ferritin heavy chain 1), HMOX1 (heme oxygenase 1), HSBP1 (heat shock factor binding protein 1), IREB2 (iron responsive element binding protein 2), NCOA4 (nuclear receptor coactivator 4), PHKG2 (phosphorylase kinase catalytic subunit gamma 2), STEAP3 (six transmembrane epithelial antigen of the prostate 3), TFRC (transferrin receptor)

Lorrain D