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Role of oxidants/antioxidants in smoking-induced lung diseases

GHRH receptor (class II GPCR) couples to Gs proteins, activating adenylyl cyclase to increase cAMP, which activates PKA

Together, studies discussed highlight how nanoformulation strategies may enhance the efficacy, bioavailability, and tumor-targeting of repurposed drugs, while simultaneously modulating the tumor microenvironment and antitumor immunity

doi: 10.1046/j.1365-2567.1999.00764.x 183 LaumonnierYKarstenCMKhlJ

For example, autophagy inhibits tumor initiation by eliminating potential oncogenic proteins and impaired organelles that cause genome instability (11,14)

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