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Well over 10,000 AR binding sites have been identified in CaP cells, and it has become clear that most AR target genes harbor more than 1 ARE

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For example, omega-3 fatty acids significantly decreased cardiovascular events in high-risk patients with hypertriglyceridemia, according to a double-blind, placebo-controlled research (72)

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In the same vein, it has been reported that ablation of Gpx4 in HSCs triggers anemia associated with an increase in the fraction of erythroid precursor cells and reticulocytes

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Cell 17 ChhabraY.NelsonC

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Therefore, future research efforts should be directed toward developing approaches that modulate this network signaling system as a cohesive unit

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(11) As a result, dual-energy X-ray absorptiometry (DEXA) measurements may show a relative uptick in body fat

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