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As this field evolves, interdisciplinary collaborations-spanning immunology and computational biologywill be integral to translating these insights into therapies that improve immune resilience and healthy longevity

The effects of n-acetylcysteine and/or deferoxamine on manic-like behavior and brain oxidative damage in mice submitted to the paradoxal sleep deprivation model of mania

Translational perspective: Targeting regulated cell death pathways in myocardial IRI offers multiple pharmacological entry points, ranging from upstream modulation of nutrient- and stress-sensing pathways (e.g., mTOR, AMPK, PARP-1, inflammasome components) to downstream inhibition of executioner mechanisms, such as lipid peroxidation, membrane rupture, and inflammatory caspase activation

According to the proposed catalytic pathway of pFeSAN (Fig

[DOI] [PubMed] [Google Scholar] 28.Furuta S

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