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Notably, the expression of multiple GSTs is massively activated by salicylic acid and some GST enzymes were demonstrated to be receptor proteins of salicylic acid

-GCS first ligates the -carboxyl group of L-glutamate (Glu) to the amino group of L-cysteine (Cys), which results in the production of L--glutamyl-L-cysteine (-Glu-Cys) [3]

doi: 10.1038/npp.2011.132

Chan R, Park KC, Lee MH, Lee E-S, Chang SE, Leow YH, Tay Y-K, Legarda-Montinola F, Tsai R-Y, Tsai T-H, Shek S, Kerrouche N, Thomas G, Verallo-Rowell V

Nanocurcumin alleviates insulin resistance and pancreatic deficits in polycystic ovary syndrome rats: insights on PI3K/AkT/mTOR and TNF-alpha modulations

Martineau AR, Cates CJ, Urashima M, Jensen M, Griffiths AP, Nurmatov U, et al