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Upregulation of melanin biosynthesis or increase in the number either of normal or of atypical oral mucosal melanocytes may bring about oral mucosal melanin hyperpigmentation

The worms were then washed twice with 1 PBS and mounted onto 2% agarose pads for visualization using a ZEISS Axio Observer.Z1 (ZEISS, Oberkochen, Germany) inverted microscope equipped with a ZEISS AxioCam MRc color camera and a ZEISS Plan-Apochromat 20/0.8 WD 0.55 mm air immersion objective

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Finally, to add a therapeutic bent to the narrative, the widely used antihypertensive drug amlodipine may have a PKC-mediated effect

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