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For instance, in chimeric human cerebral organoids (chCOs), astrocytes and neurons carrying the APOE4 genotype could jointly promote tau phosphorylation in neurons, closely linked to the role of APOE4 in increasing cholesterol levels and lipid droplet content, suggesting that APOE4 may affect tau phosphorylation in AD by influencing lipid metabolism

We examined if arginine synthesis was affected in deletion mutants disrupting lipoyl enzymes or lipoate metabolism

The roles of plant proteases and protease inhibitors in drought response: a review

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Determinants of pregnancy heartburn

Eliot AC, Kirsch JF