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A recent randomized controlled clinical trial in healthy older adults demonstrated that supplementation with glycine and N-acetylcysteine may support GSH biosynthesis in individuals with increased oxidative stress and compromised GSH stores (Lizzo et al
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In addition to conventional pharmaceuticals, combining polyphenols with neurotrophic factors (proteins that support the growth, survival, and differentiation of both developing and mature neurons) presents a novel therapeutic avenue [57]
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