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[PubMed] [Google Scholar] 116.Hiol A, Jonzo MD, Druet D, Comeau L

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EPA and DHA also have the capacity to disrupt cell membrane lipid rafts (thereby interfering with the transmission of proinflammatory signals into the cell), inhibit nuclear factor KB (a proinflammatory nuclear transcription factor), downregulate oxidative enzymes such as NADPH oxidase, upregulate anti-oxidative enzymes such as superoxide dismutase (SOD) and glutathione peroxidase (GPx), and modulate cell membrane fluidity, among other functions [66, 68]

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