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It is postulated that clinical symptoms, including CNS complications such as convulsion, coma and lethargy, may be triggered by the accumulation of metabolites and their acyl-CoA derivatives that disrupt intermediary metabolism [6669]
For background and my updated recommendations, see: The Symptoms of Vitamin B12 Deficiency The Optimal Vitamin B12 Dosage for Adults Healthiest Food Sources of Vitamin B12 The Optimal Vitamin B12 Dosage for Kids, Pregnancy, and Seniors The Best Type of Vitamin B12: Cyanocobalamin or Methylcobalamin
doi: 10.1158/0008-5472.CAN-09-3871 61 TousignantKDRockstrohAPoadBLJTalebiAYoungRSETaherian FardAet al
If you add carnitine, make it part of a deliberate plan: consistent training, adequate protein to preserve muscle, manageable calorie changes, and sleep
Recommended Use: Take 1-3 servings daily, preferably with meals or as directed by your healthcare professional
On the other hand, several observations cast doubt on the pivotal role of TMAO in atherosclerosis
