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Most people get enough vitamin B12 from their diet, but some people have a deficiency

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The Role of Vitamin B12 in Viral Infections: A Comprehensive Review of Its Relationship with the MuscleGutBrain Axis and Implications for SARS-CoV-2 Infection. Nutrition Reviews, 13 Nov

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Nicotinamide N-methyltransferase (NNMT) is a cytoplasmic enzyme that catalyzes the transfer of a methyl group from S-adenosyl-L-methionine (SAM, the universal methyl donor) to nicotinamide (the NAD + salvage precursor), producing 1-methylnicotinamide and S-adenosyl-L-homocysteine