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This variant leads to an amino acid substitution that may impair enzyme activity and alter local T3 availability, particularly in the brain and pituitary

[DOI] [PMC free article] [PubMed] [Google Scholar] Keefe A

However, it is important to keep in mind that MAOA more strongly affects dopamine levels in rodents than in humans

336.Wysocka E, Cofta S, Piorunek T, Dziegielewska-Gesiak S, Bryl W, Torlinski L

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In contrast to hemorrhagic strokes, ischemic strokes are currently more common, and their incidence is higher in older people