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10.1016/j.brainres.2012.09.022 Brain Res

conducted an experimental study and discovered that changes in the Hippo signaling pathway contribute to cognitive decline in streptozotocin-induced diabetic rats

Adeghate E, Ponery AS

PMID: 25906193

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If you need a wide range of doses, creating a more dilute solution (using more bac water) might give you the flexibility you need to measure both small and large amounts accurately from the same vial