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Typical Post-Injection Timeline First 24-48 hours: Mild to moderate pain at the injection site Localized warmth and redness Slight swelling around the knee Temporary stiffness or reduced range of motion Days 2-3: Gradual reduction in swelling Decreased pain and tenderness Return to normal mobility Possible spongy sensation when walking [4] The American Academy of Orthopaedic Surgeons notes that patients should avoid excessive activity, such as jogging or heavy lifting for the first 48 hours after injection [2]

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PMID 22535170

The addition of l-Cys was especially effective at increasing glutathione production, and metabolic engineering of l-Cys biosynthesis was also effective in enhancing glutathione production [11]

Consequently, simple antioxidant therapy may yield counterproductive effects in the treatment of complex diseases