bpc-157 brain-gut axis & The Gut-Brain Axis: A Practitioner's Definitive Review of the Evidence Peptides and the Gut–Brain Axis:

Bala et al analysed and compared B-12 levels in ASD (n=34) [22], ADHD (n=16) and controls (n=27) and noted that the ASD group had the lowest vitamin B12 levels, whereas the vitamin B12 levels of the ADHD group were significantly lower compared to the controls

[DOI] [PMC free article] [PubMed] [Google Scholar] Chong S

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High-Dose Folinic Acid (Leucovorin) Therapy Dosage: 1-2 mg/kg/day, up to 50 mg/day (split into two doses)

This study was the first longitudinal assessment of a marker of intestinal permeability in non-human primates or humans and provides the first evidence that intestinal permeability does increase over time in the context of hypertension

For individuals with mild deficiencies or as a maintenance option after injections, oral B12 supplements or sublingual B12 formulations may be suitable alternatives