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In conclusion, astrocytes capacity to clear toxic damaged proteins is critical to preserve neuronal function and their dysfunction contributes to the neurodegeneration observed in a DJ1 loss-of-function PD model
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Thus, inhibition of the thioredoxin system has been considered a strategy in the study of antitumor therapies [20]
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doi: 10.1016/j.tem.2023.06.002 [DOI] [PubMed] [Google Scholar] 218
