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In medicine, when a prescribed substance is believed to have caused an adverse effect (such as weight gain), its reported - meaning its publicly registered so physicians and scientists can learn about it and be on the lookout for similar problems

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Wang H, Chen W, Li D, et al

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Malpractice Exposure: Administering an unapproved Category 2 substance lacking human clinical trials severely compromises a physician's defense in a medical malpractice suit

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