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This review highlights how antimicrobial peptides, angiogenic peptides, cell-penetrating peptides, and ECM-mimetic peptides (ECM = extracellular matric) are being engineered into hydrogels, nanofibers, and smart dressings to overcome limitations of traditional wound therapies

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Foundational work from the 1980s by Maquart and colleagues, conducted in animal and cell models, found that GHK-Cu significantly stimulated collagen, proteoglycans, angiogenesis, and wound closure, laying the groundwork for decades of subsequent research

doi: 10.3390/molecules201119656 137

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