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Journal of Clinical Medicine, 12 (1), 145

[DOI] [PubMed] [Google Scholar] 80.Prizment AE, Staley C, Onyeaghala GC, Vivek S, Thyagarajan B, Straka RJ, Demmer RT, Knights D, Meyer KA, Shaukat A, et al

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Proper dosage, timing, and product quality are all critical factors

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However, chemical inhibition of lactate production via LDH inhibitors diminishes Treg cell function in the TME by suppressing MOESIN Kla, ultimately enhancing the HCC response to anti-PD-1 treatment