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Interindividual variance between organisms may account for the variation in the response to chemical exposure and the extent or type of observed toxic effects

doi: 10.1126/sciadv.aav7769 106 KawaguchiKHanQLiSTanYIgarashiKMurakamiTet al

One study found that people taking opiates (some of which contain acetaminophen) were 95 percent more likely to be obese and 63 percent more likely to have hypertension

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714,715 For example, as an SRT, miglustat has been used to inhibit glucosylceramide synthase to reduce the lysosomal sphingolipid load and is an approved treatment for NiemannPick type C 716