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L-glutathione is the specific isomer, while reduced glutathione refers to its chemical state

doi: 10.3389/fphar.2022.828565

Tsouros DC, Bibi S, Sarigiannidis PG

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A placebo-controlled, double-blind randomized clinical-trial (RCT) of glycine-NAC supplementation in older adults suggests the treatment:[vii] Significantly improved Glutathione deficiency Gait-speed Muscle-strength Exercise-capacity Corrected impaired mitochondrial fuel oxidation Reduced Oxidative stress Inflammation Insulin-resistance Supplementation with glutathione itself may not be effective as the tripeptide may be destroyed by the gastric acid